SCHEMBL31444703

SCHEMBL31444703

CNC(=O)CCC1Oc2cc(N)ccc2N(C)C1=O

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
F2 P00734 10/20 0.37
F10 P00742 9/20 0.37
BRD4 O60885 1/20 0.36
ITGB3 P05106 3/20 0.35
ITGA2B P08514 3/20 0.35
CREBBP Q92793 1/20 0.31
RIPK1 Q13546 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444676 1.00 F2 (0.37) F2F10BRD4ITGB3ITGA2B
SCHEMBL31444786 0.87 F2 (0.44) F2F10BRD4ITGB3ITGA2B
SCHEMBL31444654 0.75 BCL6 (0.41)
SCHEMBL8147718 0.71 PDE3B (0.41) F10BRD4ALDH1A1MEN1KMT2A
SCHEMBL17434009 0.68 BRD4 (0.42) BRD4CREBBPL3MBTL1
SCHEMBL31444632 0.68 PLK1 (0.50) ALDH1A1MEN1KMT2A
SCHEMBL17434322 0.65 HSD17B10 (0.43) BRD4CREBBPALDH1A1SMN1; SMN2MEN1
SCHEMBL14507328 0.65 PPARG (0.42) ALDH1A1SMN1; SMN2L3MBTL1
SCHEMBL17433950 0.64 HTT (0.47) BRD4CREBBPALDH1A1SMN1; SMN2KMT2A
SCHEMBL3602608 0.64 REN (0.37) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096710-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 WO disclosed