Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31445364 | 0.84 | BCHE (0.40) | TSHRMAPK1ALDH1A1POLBKDM4E | |
| SCHEMBL8281045 | 0.83 | TSHR (0.45) | TSHRMAPK1ALDH1A1POLBKDM4E | |
| SCHEMBL8281041 | 0.80 | TSHR (0.43) | TSHRMAPK1ALDH1A1POLBKDM4E | |
| SCHEMBL14981206 | 0.77 | TSHR (0.45) | TSHRMAPK1ALDH1A1POLBKDM4E | |
| SCHEMBL21107307 | 0.75 | SLC6A2 (0.42) | TSHRMAPK1ALDH1A1POLBKDM4E | |
| SCHEMBL17700680 | 0.75 | CETP (0.41) | TSHRMAPK1ALDH1A1POLBKDM4E | |
| SCHEMBL7338804 | 0.74 | TSHR (0.46) | TSHRMAPK1ALDH1A1POLBKDM4E | |
| SCHEMBL28586963 | 0.74 | ALDH1A1 (0.40) | TSHRMAPK1ALDH1A1POLBKDM4E | |
| SCHEMBL10318991 | 0.73 | SLC6A4 (0.47) | POLBNPC1SLC6A4ADRA1ASLC6A3 | |
| SCHEMBL28990480 | 0.73 | EPHX1 (0.48) | TSHRALDH1A1KDM4ECNR2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |