Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23886543 | 0.80 | NAPRT (0.43) | TRPM8NAPRTKMT2APOLBLMNA | |
| SCHEMBL3741239 | 0.80 | SMN1; SMN2 (0.42) | AKR1C3AKR1C2NAPRTPTGS1PTGS2 | |
| SCHEMBL30370713 | 0.80 | NAPRT (0.43) | TRPM8NAPRTKMT2APOLBLMNA | |
| Hydrochloric Acid SCHEMBL30370512 | 0.79 | NAPRT (0.42) | TRPM8NAPRTKMT2APOLBLMNA | |
| Hydrochloric Acid SCHEMBL23886539 | 0.79 | NAPRT (0.42) | TRPM8NAPRTKMT2APOLBLMNA | |
| SCHEMBL18989970 | 0.79 | NAPRT (0.42) | AKR1C3AKR1C2NAPRTPTGS1PTGS2 | |
| SCHEMBL3746240 | 0.79 | CXCL8 (0.42) | AKR1C3AKR1C2PTGS1PTGS2MEN1 | |
| SCHEMBL9963324 | 0.78 | CYP2D6 (0.40) | TRPM8NAPRTL3MBTL1CNR1 | |
| SCHEMBL895816 | 0.78 | AKR1C3 (0.41) | AKR1C3AKR1C2TRPM8NAPRTLMNA | |
| SCHEMBL17061189 | 0.78 | CTSA (0.45) | TRPM8NAPRTCYP1A2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |