Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 9/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 7/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171518 | 0.82 | NAMPT (0.37) | GRIN2BGRIN1CYP2D6CXCR4 | |
| SCHEMBL29482177 | 0.78 | IDH1 (0.38) | CXCR4 | |
| SCHEMBL29482176 | 0.78 | IDH1 (0.38) | CXCR4 | |
| SCHEMBL5503721 | 0.77 | IDH1 (0.37) | CXCR4 | |
| Hydrochloric Acid SCHEMBL31583264 | 0.74 | HTR2A (0.32) | — | |
| Hydrochloric Acid SCHEMBL31582728 | 0.74 | HTR2A (0.32) | — | |
| SCHEMBL8325895 | 0.74 | DRD2 (0.38) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL20140369 | 0.73 | GRIN1 (0.31) | GRIN2BGRIN1 | |
| SCHEMBL20140149 | 0.73 | GRIN1 (0.31) | GRIN2BGRIN1 | |
| SCHEMBL29797292 | 0.73 | GRIN1 (0.31) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |