Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487389 | 0.88 | FFAR4 (0.42) | APPCYP2C19CYP2C9CYP3A4FFAR4 | |
| SCHEMBL31446029 | 0.82 | HDAC4 (0.40) | FFAR4HDAC4ABL1ELOVL1 | |
| SCHEMBL1558448 | 0.81 | FFAR4 (0.39) | CYP2C19FFAR4FFAR1LPAR1 | |
| SCHEMBL2793934 | 0.78 | APP (0.48) | APPCYP2C19CYP2C9CYP3A4HDAC4 | |
| SCHEMBL28334267 | 0.77 | AKR1C1 (0.47) | HDAC4ELOVL1AKR1C1 | |
| SCHEMBL2790870 | 0.76 | HDAC3 (0.44) | APPCYP2C19CYP2C9CYP3A4HDAC4 | |
| SCHEMBL4979190 | 0.75 | PSEN1 (0.48) | APPCYP2C19CYP2C9CYP3A4HDAC4 | |
| SCHEMBL7656129 | 0.74 | ADRA1A (0.43) | CYP3A4FFAR4CYP2D6 | |
| SCHEMBL31459534 | 0.72 | HDAC4 (0.61) | APPCYP2C19CYP2C9CYP3A4HDAC4 | |
| SCHEMBL31446428 | 0.72 | AKR1C3 (0.40) | APPCYP2C19CYP2C9CYP3A4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |