⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31447288 | 0.76 | HCAR2 (0.31) | — | |
| SCHEMBL31445374 | 0.76 | HDAC9 (0.32) | — | |
| SCHEMBL31446734 | 0.75 | VNN1 (0.36) | — | |
| SCHEMBL31445640 | 0.75 | AKR1C1 (0.39) | — | |
| SCHEMBL20337750 | 0.69 | HCAR2 (0.39) | — | |
| SCHEMBL29365002 | 0.69 | HCAR2 (0.39) | — | |
| SCHEMBL31447103 | 0.69 | AKR1C1 (0.31) | — | |
| SCHEMBL18286269 | 0.66 | AKR1C1 (0.45) | — | |
| SCHEMBL31446426 | 0.66 | PDE4A (0.32) | — | |
| SCHEMBL20345734 | 0.65 | SMN1; SMN2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642782-A2 | ALPHA-V-BETA-8 INTEGRIN INHIBITORS AND USES THEREOF | Pliant Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |