Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 4/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15303924 | 0.82 | MAPT (0.43) | TOP2AGPBAR1NR1H2NR1H3PPARG | |
| SCHEMBL17022448 | 0.81 | MAPT (0.44) | TOP2AGPBAR1NR1H2NR1H3PPARG | |
| Phenanthroline SCHEMBL3137738 | 0.80 | KDM4E (0.46) | SMN1; SMN2DAOALDH1A1CTNNB1HPGD | |
| SCHEMBL6565661 | 0.79 | DAO (0.48) | SMN1; SMN2DAOALDH1A1CTNNB1WNT3A | |
| Phenanthroline SCHEMBL3137852 | 0.78 | KDM4E (0.42) | SMN1; SMN2ALDH1A1CTNNB1HPGDMAPT | |
| SCHEMBL538810 | 0.78 | DAO (0.50) | SMN1; SMN2DAOALDH1A1CTNNB1WNT3A | |
| SCHEMBL9565986 | 0.76 | DAO (0.48) | SMN1; SMN2DAOALDH1A1CTNNB1WNT3A | |
| Triphenylphosphine Oxide SCHEMBL15157249 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2DAOALDH1A1CTNNB1WNT3A | |
| Bicarbonate SCHEMBL28398978 | 0.69 | TOP2A (0.56) | TOP2AKDM4EHTTRAB9A | |
| Trifluoroacetic Acid SCHEMBL29736808 | 0.69 | TOP2A (0.51) | TOP2ANR1H2NR1H3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642996-B2 | Method of driving an organic electroluminescent device comprising a phosphorescent light emitter | ISIS INNOVATION LIMITED (GB) | 2010-01-05 | — | — | US | disclosed |
| US-20060152165-A1 | Method of driving an electroluminescent device | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2006-07-13 | — | — | US | disclosed |
| EP-1423838-A2 | METHOD OF DRIVING AN ELECTROLUMINESCENT DEVICE | Isis Innovation Limited (GB) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003021563-A2 | METHOD OF DRIVING AN ELECTROLUMINESCENT DEVICE | ISIS INNOVATION LIMITED (GB) | 2003-03-13 | — | — | WO | disclosed |