Phenanthroline

Phenanthroline

SCHEMBL3137738

O=C(CF)C(F)(F)C(=O)c1cccs1.O=C(CF)C(F)(F)C(=O)c1cccs1.O=C(CF)C(F)(F)C(=O)c1cccs1.[Eu].c1cnc2c(c1)ccc1cccnc12

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.46
ALOX15 P16050 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
EGLN1 Q9GZT9 1/20 0.38
HSP90AA1 P07900 4/20 0.38
LMNA P02545 3/20 0.38
MMP2 P08253 2/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GMNN O75496 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
MMP9 P14780 1/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
MMP8 P22894 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenanthroline SCHEMBL3137852 0.94 KDM4E (0.42) KDM4EALOX15NPSR1KMT2AMEN1
SCHEMBL6565661 0.84 DAO (0.48) KDM4EKMT2AMEN1LMNAHTT
SCHEMBL538810 0.83 DAO (0.50) KDM4EKMT2AMEN1LMNAHTT
SCHEMBL9565986 0.82 DAO (0.48) KDM4EKMT2AMEN1LMNAHTT
Phenanthroline SCHEMBL5069549 0.81 KDM4E (0.48) KDM4EALOX15NPSR1KMT2AMEN1
SCHEMBL3144739 0.80 TOP2A (0.40) KDM4ENPSR1KMT2AMEN1HSP90AA1
Phenanthroline SCHEMBL3130837 0.80 LMNA (0.43) KDM4EALOX15NPSR1KMT2AMEN1
Phenanthroline SCHEMBL6888855 0.80 MEN1 (0.47) KDM4EALOX15NPSR1KMT2AMEN1
Phenanthroline SCHEMBL3137741 0.80 MEN1 (0.47) KDM4EALOX15NPSR1KMT2AMEN1
Phenanthroline SCHEMBL3137857 0.78 KDM4E (0.48) KDM4EALOX15NPSR1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060152165-A1 Method of driving an electroluminescent device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2006-07-13 US claimed
EP-1423838-A2 METHOD OF DRIVING AN ELECTROLUMINESCENT DEVICE Isis Innovation Limited (GB) 2004-06-02 EP claimed
WO-2003021563-A2 METHOD OF DRIVING AN ELECTROLUMINESCENT DEVICE ISIS INNOVATION LIMITED (GB) 2003-03-13 WO claimed
US-7642996-B2 Method of driving an organic electroluminescent device comprising a phosphorescent light emitter ISIS INNOVATION LIMITED (GB) 2010-01-05 US disclosed
US-20060152165-A1 Method of driving an electroluminescent device CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2006-07-13 US disclosed
EP-1423838-A2 METHOD OF DRIVING AN ELECTROLUMINESCENT DEVICE Isis Innovation Limited (GB) 2004-06-02 EP disclosed
WO-2003021563-A2 METHOD OF DRIVING AN ELECTROLUMINESCENT DEVICE ISIS INNOVATION LIMITED (GB) 2003-03-13 WO disclosed