Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.49 |
| ▸ | NCS1 | P62166 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9009337 | 0.91 | CSNK1D (0.56) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL1595124 | 0.87 | ELANE (0.57) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL6286907 | 0.83 | ELANE (0.46) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL4836084 | 0.82 | ITGB1 (0.61) | ITGB1ITGA5ITGA4 | |
| SCHEMBL4458533 | 0.81 | NPC1 (0.59) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL5827952 | 0.81 | CSNK1D (0.56) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL13408929 | 0.81 | CSNK1D (0.56) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL4457424 | 0.80 | CSNK1D (0.54) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL4457418 | 0.80 | CSNK1D (0.54) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL9531007 | 0.79 | NPC1 (0.59) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833805-B1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES | ADAMED SP ZOO (PL) | 2010-02-10 | — | — | EP | disclosed |
| US-7312338-B2 | 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-12-25 | — | — | US | disclosed |
| US-20070219259-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES | ADAMED SP. Z O.O. (PL) | 2007-09-20 | — | — | US | disclosed |
| EP-1833805-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES | Adamed SP. Z O.O. (PL) | 2007-09-19 | — | — | EP | disclosed |
| US-20070088061-A1 | New 3-phenylpropionic acid derivatives | ADAMED, SP. Z.O.O. (PL) | 2007-04-19 | — | — | US | disclosed |
| WO-2006067086-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES | ADAMED SP. Z O.O. (PL) | 2006-06-29 | — | — | WO | disclosed |
| EP-1282621-B1 | VITRONECTIN RECEPTOR ANTAGONISTS | AVENTIS PHARMA SA (FR) | 2005-09-07 | — | — | EP | disclosed |
| EP-1282621-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | Aventis Pharma S.A. (FR) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001085729-A1 | NOVEL VITRONECTIN RECEPTOR ANTAGONISTS | AVENTIS PHARMA S.A. (FR) | 2001-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088061-A1 | New 3-phenylpropionic acid derivatives | PPARA, PPARD, PPARG | CSNK1D 581/4885SMN1; SMN2 3641/4885NFKB1 2799/4885 |
| US-20070219259-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES | PPARA, PPARD, PPARG | CSNK1D 541/4885SMN1; SMN2 3526/4885NFKB1 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.