Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | ELANE | P08246 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
| ▸ | RELA | Q04206 | 3/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9009399 | 1.00 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2ELANEMAPK1 | |
| Hydrochloric Acid SCHEMBL9009337 | 0.84 | CSNK1D (0.56) | NPC1RAB9ASMN1; SMN2MAPK1GAA | |
| SCHEMBL1595124 | 0.83 | ELANE (0.57) | NPC1RAB9ASMN1; SMN2ELANEMAPK1 | |
| SCHEMBL6221979 | 0.80 | ITGB1 (0.53) | NPC1RAB9ASMN1; SMN2MAPK1NFKB1 | |
| SCHEMBL6286907 | 0.79 | ELANE (0.46) | NPC1RAB9ASMN1; SMN2ELANEMAPK1 | |
| SCHEMBL4458533 | 0.79 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2MAPK1GAA | |
| SCHEMBL3144746 | 0.79 | CSNK1D (0.50) | NPC1RAB9ASMN1; SMN2GAAMEN1 | |
| SCHEMBL27383879 | 0.78 | ACP1 (0.46) | NPC1RAB9ASMN1; SMN2ELANEMAPK1 | |
| SCHEMBL9009394 | 0.76 | PTPN1 (0.50) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6958839 | 0.76 | ALDH1A1 (0.55) | NPC1RAB9ASMN1; SMN2MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5213911-A | — | — | None | — | — | JP | disclosed |
| JP-H05213911-A | LEUKOTRIENE BIOSYNTHESIS INHIBITOR | BOEHRINGER INGELHEIM PHARMACEUT INC | 1993-08-24 | — | — | JP | disclosed |