Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Fluorobenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18702923 | 0.89 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL10874458 | 0.89 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL2543676 | 0.89 | CYP3A4 (0.67) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Water SCHEMBL27604157 | 0.86 | CYP3A4 (0.63) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Bromide SCHEMBL64728 | 0.85 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Bromide SCHEMBL28046864 | 0.85 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Bromide SCHEMBL3314443 | 0.85 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Bromide SCHEMBL1409552 | 0.85 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Bromide SCHEMBL1409549 | 0.85 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Bromide SCHEMBL64729 | 0.85 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119613322-A | Circularly polarized luminescent material and preparation method thereof | 杭州惠臣科技有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119613322-A | Circularly polarized luminescent material and preparation method thereof | 杭州惠臣科技有限公司 | 2025-03-14 | — | — | CN | disclosed |