Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.73 |
| ▸ | MAOB | P27338 | 5/20 | 0.65 |
| ▸ | MAOA | P21397 | 4/20 | 0.65 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987369 | 0.94 | PTGS1 (0.67) | PTGS1PTGS2MAOBMAOACXCL12 | |
| SCHEMBL8987373 | 0.94 | PTGS1 (0.67) | PTGS1PTGS2MAOBMAOACXCL12 | |
| SCHEMBL25234231 | 0.93 | CYP3A4 (0.71) | PTGS1PTGS2MAOBMAOACXCL12 | |
| SCHEMBL3611922 | 0.93 | CYP3A4 (0.71) | PTGS1PTGS2MAOBMAOACXCL12 | |
| SCHEMBL25223264 | 0.93 | CYP3A4 (0.71) | PTGS1PTGS2MAOBMAOACXCL12 | |
| SCHEMBL28913615 | 0.92 | MAOB (0.69) | PTGS1PTGS2MAOBMAOACXCL12 | |
| SCHEMBL26103962 | 0.92 | PTGS1 (0.64) | PTGS1PTGS2MAOBMAOACXCL12 | |
| SCHEMBL26104097 | 0.92 | PTGS1 (0.64) | PTGS1PTGS2MAOBMAOACXCL12 | |
| SCHEMBL25201291 | 0.90 | PTGS1 (0.62) | PTGS1PTGS2MAOBMAOACXCL12 | |
| SCHEMBL25194322 | 0.90 | PTGS1 (0.62) | PTGS1PTGS2MAOBMAOACXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444359-B | Asymmetric double chalcone compound, synthesis method and application thereof | 温州医科大学附属眼视光医院 | 2025-03-18 | — | — | CN | disclosed |