Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | BCHE | P06276 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.58 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.57 |
| ▸ | SMO | Q99835 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987373 | 1.00 | PTGS1 (0.67) | PTGS1PTGS2MAPTBCHECYP2C19 | |
| SCHEMBL31448615 | 0.94 | PTGS1 (0.73) | PTGS1PTGS2MAPTBCHECYP2C19 | |
| SCHEMBL25201291 | 0.89 | PTGS1 (0.62) | PTGS1PTGS2MAPTBCHECYP2C19 | |
| SCHEMBL25194322 | 0.89 | PTGS1 (0.62) | PTGS1PTGS2MAPTBCHECYP2C19 | |
| SCHEMBL27741821 | 0.88 | MAPT (0.60) | PTGS1PTGS2MAPTBCHECYP2C19 | |
| SCHEMBL25223264 | 0.88 | CYP3A4 (0.71) | PTGS1PTGS2MAPTBCHECYP2C19 | |
| SCHEMBL3611922 | 0.88 | CYP3A4 (0.71) | PTGS1PTGS2MAPTBCHECYP2C19 | |
| SCHEMBL25234231 | 0.88 | CYP3A4 (0.71) | PTGS1PTGS2MAPTBCHECYP2C19 | |
| SCHEMBL5138125 | 0.86 | MAPT (0.63) | PTGS1PTGS2MAPTBCHECYP2C19 | |
| SCHEMBL28913615 | 0.86 | MAOB (0.69) | PTGS1PTGS2MAPTBCHECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461501-A | Green method for high-selectivity synthesis of chalcone compounds | 温州大学 | 2021-10-01 | — | — | CN | disclosed |
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |