Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16485169 | 0.95 | PTPN11 (0.53) | LCKLOXL2PTPN11TP53LMNA | |
| SCHEMBL3149487 | 0.85 | CYP4A11 (0.50) | LCKLOXL2PTPN11TP53CA1 | |
| SCHEMBL19829368 | 0.85 | PTPN11 (0.47) | LCKLOXL2PTPN11TP53CA1 | |
| SCHEMBL709231 | 0.84 | LCK (0.62) | LCKPTPN11TP53LMNACA1 | |
| SCHEMBL9939493 | 0.83 | CYP11B1 (0.49) | LOXL2TP53CA1CA2CA12 | |
| SCHEMBL20612436 | 0.83 | PTPN11 (0.50) | LCKLOXL2PTPN11TP53CA1 | |
| SCHEMBL13681261 | 0.83 | PTPN11 (0.50) | LCKLOXL2PTPN11TP53CA1 | |
| SCHEMBL12015399 | 0.81 | PTPN11 (0.55) | LCKLOXL2PTPN11CA1CA2 | |
| SCHEMBL10989390 | 0.81 | PTPN11 (0.49) | LCKLOXL2PTPN11CA1CA2 | |
| SCHEMBL2607023 | 0.81 | LOXL2 (0.66) | LOXL2TP53LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081825-A1 | 1-NAPHTHYL ALKYLPIPERIDINE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2010-04-01 | — | — | US | disclosed |
| CN-101595091-A | 1-naphthyl alkylpiperidine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-12-02 | — | — | CN | disclosed |
| EP-2098509-A1 | 1-NAPHTHYL ALKYLPIPERIDINE DERIVATIVE | Taisho Pharmaceutical Co. Ltd. (JP) | 2009-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081825-A1 | 1-NAPHTHYL ALKYLPIPERIDINE DERIVATIVE | MCHR1, MCHR2, MC5R | LCK 3951/4885LOXL2 3539/4885PTPN11 840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.