Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.63 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | DDO | Q99489 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31418220 | 0.90 | HCAR2 (0.56) | HCAR2MKNK1MKNK2KDM4EALDH1A1 | |
| SCHEMBL3181717 | 0.86 | MKNK1 (0.69) | HCAR2MKNK1MKNK2KDM4EALDH1A1 | |
| SCHEMBL28498113 | 0.85 | HCAR2 (0.63) | HCAR2MKNK1MKNK2KDM4EALDH1A1 | |
| SCHEMBL28134052 | 0.84 | MKNK1 (0.62) | HCAR2MKNK1MKNK2KDM4EALDH1A1 | |
| SCHEMBL31242967 | 0.84 | CYP11B2 (0.55) | HCAR2MKNK1MKNK2SCN10AABL1 | |
| SCHEMBL2900222 | 0.84 | MKNK1 (0.68) | HCAR2MKNK1MKNK2KDM4EALDH1A1 | |
| SCHEMBL27987797 | 0.84 | CYP11B2 (0.55) | HCAR2MKNK1MKNK2SCN10AABL1 | |
| SCHEMBL31475536 | 0.83 | HCAR2 (0.56) | HCAR2MKNK1MKNK2KMO | |
| SCHEMBL25544943 | 0.83 | HCAR2 (0.56) | HCAR2MKNK1MKNK2KMO | |
| SCHEMBL7079108 | 0.80 | HCAR2 (0.52) | HCAR2MKNK1MKNK2LDHAHCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743464-A1 | SOMATOSTATIN SUBTYPE RECEPTOR 3 (SSTR3) AGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025019256-A1 | SOMATOSTATIN SUBTYPE RECEPTOR 3 (SSTR3) AGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2025-01-23 | — | — | WO | disclosed |