SCHEMBL31450801

SCHEMBL31450801

CNCCNc1ccc(S(=O)(=O)NC(=O)c2ccc(N3CCN(CC4=C(c5ccc(Cl)cc5)CC(C)(C)CC4)CC3)cc2Oc2cnc3[nH]ccc3c2)cc1S(=O)(=O)C(F)(F)F

nearest known ligand 0.91

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 16/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26648038 1.00 BCL2 (0.91) BCL2
SCHEMBL26648615 0.97 BCL2 (0.89) BCL2
SCHEMBL31450968 0.97 BCL2 (0.89) BCL2
SCHEMBL26648239 0.95 BCL2 (0.89) BCL2
SCHEMBL31450902 0.95 BCL2 (0.89) BCL2
SCHEMBL30313867 0.95 BCL2 (1.00) BCL2
SCHEMBL1699798 0.95 BCL2 (1.00) BCL2
SCHEMBL31450933 0.94 BCL2 (0.89) BCL2
SCHEMBL26648683 0.94 BCL2 (0.89) BCL2
SCHEMBL31450870 0.93 BCL2 (0.87) BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4522154-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-03-19 — — EP disclosed
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