Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 15/20 | 0.87 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26648255 | 1.00 | BCL2 (0.87) | BCL2HDAC1HDAC6 | |
| SCHEMBL26648613 | 0.98 | BCL2 (0.84) | BCL2HDAC1HDAC6 | |
| SCHEMBL31450789 | 0.98 | BCL2 (0.84) | BCL2HDAC1HDAC6 | |
| SCHEMBL31450848 | 0.97 | BCL2 (0.81) | BCL2HDAC1HDAC6 | |
| SCHEMBL26648539 | 0.97 | BCL2 (0.81) | BCL2HDAC1HDAC6 | |
| SCHEMBL31450701 | 0.94 | BCL2 (0.84) | BCL2 | |
| SCHEMBL26648341 | 0.94 | BCL2 (0.84) | BCL2HDAC1HDAC6 | |
| SCHEMBL26648103 | 0.94 | BCL2 (0.84) | BCL2 | |
| SCHEMBL31450990 | 0.94 | BCL2 (0.84) | BCL2HDAC1HDAC6 | |
| SCHEMBL31450719 | 0.94 | BCL2 (0.77) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522154-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |