Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1958837 | 1.00 | BCL2L1 (0.59) | BCL2L1RAB9ACA1CA2CA9 | |
| SCHEMBL1957996 | 0.96 | BCL2L1 (0.56) | BCL2L1RAB9ACA1CA2CA9 | |
| SCHEMBL2480810 | 0.95 | BCL2L1 (0.55) | BCL2L1RAB9ACA1CA2CA9 | |
| SCHEMBL2482115 | 0.94 | BCL2L1 (0.61) | BCL2L1RAB9ACA1CA2CA9 | |
| SCHEMBL26648607 | 0.87 | CA2 (0.46) | BCL2L1RAB9ACA1CA2CA9 | |
| SCHEMBL1957998 | 0.82 | BCL2L1 (0.46) | BCL2L1RAB9APOLBMAPTPKM | |
| SCHEMBL22107026 | 0.81 | CA1 (0.54) | RAB9ACA1CA2CA9CA12 | |
| SCHEMBL26648378 | 0.81 | ACKR3 (0.44) | BCL2L1CA1CA2CA12ALDH1A1 | |
| SCHEMBL30468003 | 0.80 | MAPT (0.72) | RAB9ACA1CA2CA9CA12 | |
| SCHEMBL1699958 | 0.80 | MAPT (0.72) | RAB9ACA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522154-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |