Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 17/20 | 0.59 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3154555 | 0.88 | RAB9A (0.67) | P2RY1P2RY14MEN1NPC1RAB9A | |
| SCHEMBL3144166 | 0.88 | P2RY1 (0.65) | P2RY1P2RY14NPC1RAB9AMAPT | |
| SCHEMBL3160294 | 0.86 | P2RY1 (0.66) | P2RY1P2RY14MEN1NPC1RAB9A | |
| SCHEMBL3163201 | 0.83 | P2RY1 (0.66) | P2RY1P2RY14 | |
| SCHEMBL3155017 | 0.82 | P2RY1 (0.58) | P2RY1P2RY14MEN1NPC1RAB9A | |
| SCHEMBL1307054 | 0.79 | P2RY1 (0.59) | P2RY1 | |
| SCHEMBL3159410 | 0.79 | P2RY1 (0.58) | P2RY1P2RY14 | |
| SCHEMBL3155588 | 0.79 | P2RY1 (0.71) | P2RY1P2RY14MEN1NPC1RAB9A | |
| SCHEMBL1308822 | 0.79 | P2RY1 (0.66) | P2RY1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL3157678 | 0.77 | P2RY1 (0.67) | P2RY1P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751113-B1 | UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB CO (US) | 2010-03-10 | — | — | EP | claimed |