Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 5/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | BCL2 | P10415 | 3/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26647739 | 1.00 | MEN1 (0.35) | MEN1KMT2ALMNARXFP1GPR119 | |
| SCHEMBL26648243 | 0.91 | CNR1 (0.35) | MEN1KMT2ALMNARXFP1GPR119 | |
| SCHEMBL26648660 | 0.89 | MAPT (0.39) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL26647941 | 0.89 | MAPT (0.39) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL26647936 | 0.89 | MAPT (0.39) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL554341 | 0.86 | TP53 (0.39) | CNR1CNR2BCL2BCL2L1USP2 | |
| SCHEMBL554340 | 0.86 | TP53 (0.39) | CNR1CNR2BCL2BCL2L1USP2 | |
| SCHEMBL553496 | 0.85 | BCL2 (0.41) | BCL2BCL2L1USP2ENPP2TP53 | |
| SCHEMBL553495 | 0.85 | BCL2 (0.41) | BCL2BCL2L1USP2ENPP2TP53 | |
| SCHEMBL31450817 | 0.85 | F10 (0.40) | MEN1KMT2ASMN1; SMN2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522154-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |