Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 19/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31451785 | 0.93 | KRAS (0.39) | KRASSOS1AXL | |
| SCHEMBL31451679 | 0.88 | KRAS (0.40) | KRASSOS1 | |
| SCHEMBL31451727 | 0.87 | KRAS (0.38) | KRASSOS1 | |
| SCHEMBL31451798 | 0.85 | KRAS (0.41) | KRASSOS1 | |
| SCHEMBL31451817 | 0.85 | KRAS (0.41) | KRASSOS1 | |
| SCHEMBL31451838 | 0.85 | KRAS (0.40) | KRASSOS1 | |
| SCHEMBL31451787 | 0.84 | KRAS (0.45) | KRASAXL | |
| SCHEMBL31451734 | 0.84 | KRAS (0.45) | KRASSOS1 | |
| SCHEMBL31451753 | 0.83 | KRAS (0.43) | KRASSOS1 | |
| SCHEMBL31451475 | 0.83 | KRAS (0.46) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016899-A1 | SPIROCYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2025-01-23 | — | — | WO | claimed |
| WO-2025016899-A1 | SPIROCYCLIC COMPOUNDS FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2025-01-23 | — | — | WO | disclosed |