SCHEMBL31451982

SCHEMBL31451982

CNC(=O)c1ncn2c(=O)n(CCF)nnc12

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
PABPC1 P11940 1/20 0.47
KMT2A Q03164 1/20 0.47
CA12 O43570 3/20 0.43
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA9 Q16790 3/20 0.43
CYP2C9 P11712 1/20 0.34
GAA P10253 1/20 0.34
YTHDC1 Q96MU7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3336603 0.88 MEN1 (0.47) MEN1PABPC1KMT2ACA12CA1
Water SCHEMBL10648619 0.86 MEN1 (0.46) MEN1PABPC1KMT2ACA12CA1
SCHEMBL22847416 0.86 MEN1 (0.47) MEN1PABPC1KMT2ACA12CA1
SCHEMBL14980053 0.86 MEN1 (0.47) MEN1PABPC1KMT2ACA12CA1
SCHEMBL13028034 0.83 MEN1 (0.64) MEN1PABPC1KMT2ACA12CA1
SCHEMBL25434536 0.81 MEN1 (0.43) MEN1PABPC1KMT2ACA12CA1
SCHEMBL7876576 0.81 MEN1 (0.69) MEN1PABPC1KMT2ACA12CA1
SCHEMBL26321485 0.81 MEN1 (0.42) MEN1PABPC1KMT2ACA12CA1
SCHEMBL14980051 0.81 MEN1 (0.42) MEN1PABPC1KMT2ACA12CA1
SCHEMBL13027731 0.74 MEN1 (0.71) MEN1PABPC1KMT2ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066371-A1 FLUOROALKOXYALKYLENE-DIHYDROIMIDAZO[5,1-D]TETRAZINONE COMPOUNDS AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS MODIFI BIOSCIENCES, INC. 2025-02-27 US disclosed
WO-2025034537-A1 FLUOROALKOXYALKYLENE-DIHYDROIMIDAZO[5,1-D]TETRAZINONE COMPOUNDS AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS MODIFI BIOSCIENCES, INC. (US) 2025-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066371-A1 FLUOROALKOXYALKYLENE-DIHYDROIMIDAZO[5,1-D]TETRAZINONE COMPOUNDS AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS PKD1, APC, VHL MEN1 1199/4885PABPC1 4026/4885KMT2A 2741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.