SCHEMBL31452014

SCHEMBL31452014

Cc1ncn2c(=O)n(CCOC(F)(F)F)nnc12

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.34
MEN1 O00255 1/20 0.34
PABPC1 P11940 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31451974 0.85 MEN1 (0.32) BRD4MEN1PABPC1KMT2A
SCHEMBL31452096 0.83 MEN1 (0.44) BRD4MEN1PABPC1KMT2A
SCHEMBL31452100 0.82 MEN1 (0.41) MEN1PABPC1KMT2A
SCHEMBL31452039 0.81 KDM5A (0.31)
SCHEMBL31451983 0.81 KMT2A (0.45) BRD4MEN1PABPC1KMT2A
SCHEMBL31452056 0.81 MEN1 (0.56) BRD4MEN1PABPC1KMT2A
SCHEMBL31452072 0.81 MEN1 (0.41) BRD4MEN1PABPC1KMT2A
SCHEMBL31452105 0.81 MEN1 (0.44) BRD4MEN1PABPC1KMT2A
SCHEMBL31452009 0.80 MEN1 (0.42) BRD4MEN1PABPC1KMT2A
SCHEMBL31451975 0.80 PTGER4 (0.35) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066371-A1 FLUOROALKOXYALKYLENE-DIHYDROIMIDAZO[5,1-D]TETRAZINONE COMPOUNDS AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS MODIFI BIOSCIENCES, INC. 2025-02-27 US disclosed
WO-2025034537-A1 FLUOROALKOXYALKYLENE-DIHYDROIMIDAZO[5,1-D]TETRAZINONE COMPOUNDS AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS MODIFI BIOSCIENCES, INC. (US) 2025-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066371-A1 FLUOROALKOXYALKYLENE-DIHYDROIMIDAZO[5,1-D]TETRAZINONE COMPOUNDS AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS PKD1, APC, VHL BRD4 693/4885MEN1 1199/4885PABPC1 4026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.