Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.38 |
| ▸ | FOS | P01100 | 6/20 | 0.38 |
| ▸ | JUN | P05412 | 6/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.38 |
| ▸ | RELA | Q04206 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17764556 | 0.84 | SYK (0.51) | SYKRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL11582959 | 0.82 | SYK (0.49) | SYKRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL654492 | 0.82 | SYK (0.49) | SYKRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL31679507 | 0.82 | ALDH1A1 (0.53) | SYKRAB9AALDH1A1NPC1L3MBTL1 | |
| SCHEMBL654750 | 0.80 | SYK (0.48) | SYKRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL27631703 | 0.80 | SYK (0.48) | SYKRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL655671 | 0.79 | SYK (0.47) | SYKRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL27612355 | 0.79 | SYK (0.47) | SYKRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL23620399 | 0.78 | SYK (0.54) | SYKALDH1A1NPC1KDM4ENFKB1 | |
| SCHEMBL14810384 | 0.78 | KDM4E (0.57) | SYKALDH1A1NPC1KDM4ENFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250049809-A1 | INHIBITORS OF MUTANT IDH1 AND IDH2 | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2025-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250049809-A1 | INHIBITORS OF MUTANT IDH1 AND IDH2 | IDH1, IDH2, IDH3A | SYK 3341/4885RAB9A 1885/4885ALDH1A1 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.