Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | GP6 | Q9HCN6 | 2/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3774366 | 0.99 | IDO1 (0.41) | IDO1GP6SLC22A12CREBBPMRGPRX4 | |
| SCHEMBL3150837 | 0.91 | MAP4K4 (0.43) | MRGPRX4HPGDSALDH1A1XDHMAP4K4 | |
| Hydrochloric Acid SCHEMBL3154957 | 0.90 | MAP4K4 (0.43) | MRGPRX4HPGDSALDH1A1XDHMAP4K4 | |
| SCHEMBL3151049 | 0.85 | EGLN1 (0.43) | IDO1GP6SLC22A12CREBBPEGLN1 | |
| Hydrochloric Acid SCHEMBL3774374 | 0.83 | IDO1 (0.40) | IDO1GP6SLC22A12CREBBPMRGPRX4 | |
| SCHEMBL3155932 | 0.82 | DHFR (0.39) | — | |
| SCHEMBL3777217 | 0.81 | CREBBP (0.40) | IDO1GP6SLC22A12CREBBPEGLN1 | |
| SCHEMBL3154920 | 0.81 | MAP4K4 (0.35) | MAP4K4 | |
| Hydrochloric Acid SCHEMBL3767963 | 0.81 | DHFR (0.38) | — | |
| SCHEMBL3155946 | 0.81 | FFAR4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |