Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27191543 | 0.97 | HSD17B10 (0.34) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| Hydrochloric Acid SCHEMBL30568993 | 0.95 | CYP2D6 (0.33) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| SCHEMBL29256163 | 0.88 | CYP2D6 (0.34) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| SCHEMBL28386617 | 0.88 | SMN1; SMN2 (0.32) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| SCHEMBL27772851 | 0.86 | FFAR3 (0.32) | CYP2D6CYP2C19POLBCYP2C9KMT2A | |
| Nitric Acid SCHEMBL28394768 | 0.84 | CA5A (0.33) | KMT2AALDH1A1APEX1LMNA | |
| Bromide SCHEMBL28157432 | 0.84 | HTT (0.32) | HTT | |
| SCHEMBL28801345 | 0.83 | KDM4E (0.31) | L3MBTL1KDM4E | |
| SCHEMBL27766124 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL28804720 | 0.81 | KDM4E (0.30) | SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751907-A | Preparation method of metal organic framework based on ionic liquid, product and application of metal organic framework in carbon dioxide cycloaddition reaction | 杭州医学院 | 2025-04-04 | — | — | CN | disclosed |