Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1163011 | 0.86 | ALDH1A1 (0.43) | ALDH1A1CYP2C19MAPTHTTGAA | |
| SCHEMBL31453130 | 0.86 | ALDH1A1 (0.46) | ALDH1A1CYP2C19MAPTHTTGAA | |
| SCHEMBL31453190 | 0.85 | ALDH1A1 (0.42) | ALDH1A1CYP2C19MAPTHTTGAA | |
| SCHEMBL9909962 | 0.85 | ALDH1A1 (0.42) | ALDH1A1CYP2C19MAPTHTTGAA | |
| SCHEMBL31453153 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CYP2C19MAPTHTTGAA | |
| SCHEMBL31453237 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP2C19MAPTHTTGAA | |
| SCHEMBL29126475 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CYP2C19MAPTHTTCRHBP | |
| SCHEMBL31453189 | 0.81 | ALDH1A1 (0.39) | ALDH1A1CYP2C19MAPTHTTGAA | |
| SCHEMBL26310184 | 0.80 | AAK1 (0.37) | ALDH1A1CYP2C19MAPTHTTGAA | |
| SCHEMBL25522858 | 0.78 | CYP2C19 (0.44) | ALDH1A1CYP2C19MAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051157-A1 | PYRIDINE-2(1H)-KETONE PRMT5-MTA INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2025-03-13 | — | — | WO | disclosed |