SCHEMBL3145348

SCHEMBL3145348

CCCCCCCCCCOC1CCCS1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 3/20 0.40
ALDH1A1 P00352 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NAAA Q02083 2/20 0.35
MEN1 O00255 1/20 0.34
THRB P10828 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.34
CA1 P00915 8/20 0.33
CA2 P00918 8/20 0.33
CA9 Q16790 7/20 0.33
CA12 O43570 3/20 0.33
CA7 P43166 3/20 0.33
CA14 Q9ULX7 3/20 0.33
CA3 P07451 2/20 0.33
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33
CA5A P35218 2/20 0.33
CA5B Q9Y2D0 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7569036 0.98 GBA1 (0.37) GBA1ALDH1A1TDP1NAAAMEN1
SCHEMBL13864496 0.86 GBA1 (0.36) GBA1ALDH1A1TDP1NAAAMEN1
SCHEMBL2115184 0.84
SCHEMBL20601576 0.76
SCHEMBL29239966 0.73 ALDH1A1 (0.49) ALDH1A1TDP1MEN1THRBHTT
SCHEMBL5935738 0.73 ALDH1A1 (0.49) ALDH1A1TDP1MEN1THRBHTT
SCHEMBL7569046 0.70 MEN1 (0.42) GBA1ALDH1A1TDP1MEN1THRB
SCHEMBL19678784 0.70 GBA1 (0.49) GBA1ALDH1A1TDP1NAAAMEN1
SCHEMBL3181641 0.70 GBA1 (0.49) GBA1ALDH1A1TDP1NAAAMEN1
SCHEMBL3181823 0.70 GBA1 (0.49) GBA1ALDH1A1TDP1NAAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2046926-B1 MULTI-DISPERSANT LUBRICATING COMPOSITION LUBRIZOL CORP (US) 2018-06-13 EP disclosed
US-8598099-B2 Multi-dispersant lubricating composition THE LUBRIZOL CORPORATION (US) 2013-12-03 US disclosed
US-20130102511-A1 Additive Concentrate and a Method of Lubricating Transmissions THE LUBRIZOL CORPORATION (US) 2013-04-25 US disclosed
US-20120178661-A1 Additive Concentrate and a Method of Lubricating Transmissions THE LUBRIZOL CORPORATION (US) 2012-07-12 US disclosed
US-20120135898-A1 Multi-Dispersant Lubricating Composition THE LUBRIZOL CORPORATION (US) 2012-05-31 US disclosed
US-20100099593-A1 Additive Concentrate and a Method of Lubricating Transmissions THE LUBRIZOL CORPORATION 2010-04-22 US disclosed
EP-1200541-B1 NITROGEN-CONTAINING ESTERIFIED CARBOXY-CONTAINING INTERPOLYMERS HAVING ENHANCED OXIDATIVE STABILITY AND LUBRICANTS CONTAINING THEM LUBRIZOL CORP (US) 2010-02-10 EP disclosed
US-20090305919-A1 Multi-Dispersant Lubricating Composition THE LUBRIZOL CORPORATION (US) 2009-12-10 US disclosed
EP-2046926-A2 MULTI-DISPERSANT LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2009-04-15 EP disclosed
WO-2008115726-A2 ADDITIVE CONCENTRATE AND A METHOD OF LUBRICATING TRANSMISSIONS THE LUBRIZOL CORPORATION (US) 2008-09-25 WO disclosed
WO-2008014319-A2 MULTI-DISPERSANT LUBRICATING COMPOSITION THE LUBRIZOL CORPORATION (US) 2008-01-31 WO disclosed
US-6544935-B1 Useful as viscosity improvers THE LUBRIZOL CORPORATION 2003-04-08 US disclosed
EP-1200541-A1 NITROGEN-CONTAINING ESTERIFIED CARBOXY-CONTAINING INTERPOLYMERS HAVING ENHANCED OXIDATIVE STABILITY AND LUBRICANTS CONTAINING THEM The Lubrizol Corporation (US) 2002-05-02 EP disclosed
WO-2001004242-A1 NITROGEN-CONTAINING ESTERIFIED CARBOXY-CONTAINING INTERPOLYMERS HAVING ENHANCED OXIDATIVE STABILITY AND LUBRICANTS CONTAINING THEM THE LUBRIZOL CORPORATION (US) 2001-01-18 WO disclosed