Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 2/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17678202 | 0.87 | CDK9 (0.51) | CDK9CCNT1MCHR1KDM4EALDH1A1 | |
| SCHEMBL30847394 | 0.87 | CDK9 (0.51) | CDK9CCNT1MCHR1KDM4EALDH1A1 | |
| SCHEMBL2493364 | 0.85 | CDK9 (0.60) | CDK9CCNT1MCHR1KDM4EALDH1A1 | |
| SCHEMBL17586642 | 0.85 | CDK9 (0.56) | CDK9CCNT1MCHR1KDM4EALDH1A1 | |
| SCHEMBL19698020 | 0.83 | CDK9 (0.58) | CDK9CCNT1MCHR1KDM4EALDH1A1 | |
| SCHEMBL19703388 | 0.81 | CDK9 (0.46) | CDK9CCNT1MCHR1KDM4EALDH1A1 | |
| SCHEMBL15206670 | 0.81 | CDK9 (0.46) | CDK9CCNT1MCHR1KDM4EALDH1A1 | |
| SCHEMBL15206671 | 0.81 | CDK9 (0.46) | CDK9CCNT1MCHR1KDM4EALDH1A1 | |
| SCHEMBL25523015 | 0.81 | CDK9 (0.46) | CDK9CCNT1MCHR1KDM4EALDH1A1 | |
| SCHEMBL29547847 | 0.78 | MCHR1 (0.42) | CDK9CCNT1MCHR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707925-A | Compounds as KIF18A inhibitors and uses thereof | 南京圣和药物研发有限公司 | 2025-03-28 | — | — | CN | disclosed |