SCHEMBL31454583

SCHEMBL31454583

Cn1nccc1C(=O)N=C=S

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.45
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
RAB9A P51151 5/20 0.42
NPC1 O15118 4/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 3/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
NAMPT P43490 1/20 0.40
PKM P14618 3/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.38
GPR52 Q9Y2T5 1/20 0.38
PIK3CD O00329 1/20 0.37
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23005655 0.77 HTT (0.49) HTTKMT2AL3MBTL1RAB9ANPC1
SCHEMBL27278396 0.73 HTT (0.67) HTTKMT2AL3MBTL1RAB9ANPC1
SCHEMBL335332 0.71
SCHEMBL15836938 0.70
SCHEMBL892658 0.70
Lithium Ion SCHEMBL30968154 0.68 HTT (0.51) HTTKMT2AL3MBTL1RAB9ANPC1
SCHEMBL32678630 0.67 HTT (0.40) HTTKMT2AL3MBTL1RAB9ANPC1
SCHEMBL32678629 0.67 HTT (0.40) HTTKMT2AL3MBTL1RAB9ANPC1
SCHEMBL32678632 0.67 HTT (0.40) HTTKMT2AL3MBTL1RAB9ANPC1
SCHEMBL31454669 0.67 KDM4E (0.43) RAB9ANPC1ALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250108048-A1 STING AGONIST COMPOUNDS AND CONJUGATES SUTRO BIOPHARMA, INC. 2025-04-03 US disclosed
WO-2025029832-A2 STING AGONIST COMPOUNDS AND CONJUGATES SUTRO BIOPHARMA, INC. (US) 2025-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250108048-A1 STING AGONIST COMPOUNDS AND CONJUGATES STING1, CGAS, MAVS HTT 2644/4885KMT2A 3278/4885L3MBTL1 1274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.