Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25385310 | 0.83 | ABCG2 (0.61) | PDE5AABCC1ABCG2KDM4EALDH1A1 | |
| SCHEMBL31455169 | 0.83 | ABCG2 (0.61) | PDE5AABCC1ABCG2KDM4EALDH1A1 | |
| SCHEMBL31455412 | 0.83 | GSK3B (0.43) | PDE5AABCC1ABCG2MAPK1JAK2 | |
| SCHEMBL31455225 | 0.78 | NPC1 (0.44) | PDE5AABCC1ABCG2MAP2K3KDM4E | |
| SCHEMBL25161861 | 0.77 | HDAC2 (0.48) | HDAC2KDM4EALDH1A1HPGDJAK2 | |
| SCHEMBL31455924 | 0.77 | HDAC2 (0.41) | PDE5AABCC1ABCG2PIK3CAHDAC2 | |
| SCHEMBL31455195 | 0.77 | HDAC1 (0.45) | ABCG2MAP2K3PIK3CAHDAC2 | |
| SCHEMBL30615600 | 0.75 | MAPT (0.49) | MAPK1HDAC2KDM4EALDH1A1HPGD | |
| SCHEMBL28495315 | 0.75 | MAPT (0.49) | MAPK1HDAC2KDM4EALDH1A1HPGD | |
| SCHEMBL25161885 | 0.75 | HDAC1 (0.49) | MAPK1HDAC2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |