Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455719 | 0.83 | ABCG2 (0.45) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL31227501 | 0.82 | ABL1 (0.44) | ALDH1A1KDM4EMAPTGAAHPGD | |
| SCHEMBL25385310 | 0.82 | ABCG2 (0.61) | SMN1; SMN2ABCG2PDE5AABCC1ALDH1A1 | |
| SCHEMBL31455169 | 0.82 | ABCG2 (0.61) | SMN1; SMN2ABCG2PDE5AABCC1ALDH1A1 | |
| SCHEMBL31455120 | 0.78 | PDE5A (0.43) | NPC1RAB9ASMN1; SMN2ABCG2PDE5A | |
| SCHEMBL31455275 | 0.78 | BRD9 (0.43) | SMN1; SMN2ABCG2MEN1KMT2AMAP2K3 | |
| SCHEMBL16608985 | 0.76 | MAPT (0.55) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL31455688 | 0.76 | ABCG2 (0.39) | ABCG2SYKHDAC1 | |
| SCHEMBL31455924 | 0.76 | HDAC2 (0.41) | NPC1RAB9ASMN1; SMN2ABCG2PDE5A | |
| SCHEMBL16645313 | 0.75 | HDAC1 (0.57) | RAB9ASMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |