Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 13/20 | 0.56 |
| ▸ | AKT2 | P31751 | 8/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AKT3 | Q9Y243 | 5/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455298 | 0.83 | AKT1 (0.53) | AKT1AKT2AOC3AKT3 | |
| SCHEMBL31455458 | 0.81 | AKT1 (0.49) | AKT1AKT2MAPTAKT3 | |
| SCHEMBL31455115 | 0.81 | AKT1 (0.48) | AKT1AKT2MAPTSMN1; SMN2AKT3 | |
| SCHEMBL31455276 | 0.81 | AKT1 (0.48) | AKT1AKT2MAPTSMN1; SMN2AKT3 | |
| SCHEMBL31455214 | 0.79 | AKT1 (0.47) | AKT1AKT2MAPTAKT3 | |
| SCHEMBL31455131 | 0.78 | AKT1 (0.65) | AKT1AKT2AKT3 | |
| SCHEMBL25386232 | 0.75 | AKT1 (0.63) | AKT1AKT2AKT3 | |
| SCHEMBL30574959 | 0.75 | AKT1 (0.63) | AKT1AKT2AKT3 | |
| SCHEMBL30574962 | 0.75 | AKT1 (0.63) | AKT1AKT2AKT3 | |
| SCHEMBL25384795 | 0.74 | AKT1 (0.71) | AKT1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |