Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 17/20 | 0.53 |
| ▸ | AKT2 | P31751 | 11/20 | 0.44 |
| ▸ | AKT3 | Q9Y243 | 6/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455404 | 0.83 | AKT1 (0.48) | AKT1AKT2AKT3 | |
| SCHEMBL31455520 | 0.83 | AKT1 (0.48) | AKT1AKT2AKT3 | |
| SCHEMBL31455230 | 0.83 | AKT1 (0.56) | AKT1AKT2AKT3AOC3 | |
| SCHEMBL31455457 | 0.82 | AKT1 (0.47) | AKT1AKT2AKT3 | |
| SCHEMBL31455571 | 0.81 | AKT1 (0.47) | AKT1AKT2AKT3 | |
| SCHEMBL31455131 | 0.75 | AKT1 (0.65) | AKT1AKT2AKT3 | |
| SCHEMBL31455193 | 0.73 | AKT1 (0.46) | AKT1AKT2AKT3 | |
| SCHEMBL27227277 | 0.72 | AKT1 (0.55) | AKT1AKT2AKT3 | |
| SCHEMBL31455033 | 0.72 | AKT1 (0.42) | AKT1AKT2AKT3AOC3 | |
| SCHEMBL31455224 | 0.72 | AKT1 (0.45) | AKT1AKT2AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |