Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TLR4 | O00206 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503392 | 0.88 | MAPT (0.49) | TDP1TLR4TLR2MAPTRAB9A | |
| SCHEMBL13736898 | 0.82 | MAPT (0.49) | TDP1ATMTLR4TLR2MAPT | |
| SCHEMBL12643379 | 0.79 | MAPT (0.69) | TDP1TLR4TLR2MAPTRAB9A | |
| SCHEMBL8302605 | 0.79 | MAPT (0.62) | TDP1TLR4TLR2MAPTRAB9A | |
| SCHEMBL6974757 | 0.79 | AURKB (0.50) | TDP1TLR4TLR2MAPTRAB9A | |
| SCHEMBL3031212 | 0.79 | MAPT (0.63) | TLR4TLR2MAPTRAB9ANPC1 | |
| SCHEMBL18553627 | 0.78 | MAPT (0.46) | TDP1ATMTLR4TLR2MAPT | |
| SCHEMBL16473340 | 0.78 | TDP1 (0.45) | TDP1ATMMAPTRAB9ANPC1 | |
| SCHEMBL6508859 | 0.78 | MAPT (0.42) | TDP1TLR4TLR2MAPTRAB9A | |
| SCHEMBL31375722 | 0.77 | TDP1 (0.58) | TDP1ATMMAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |