Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TLR4 | O00206 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508859 | 0.89 | MAPT (0.42) | MAPTRAB9ANPC1TLR4TLR2 | |
| SCHEMBL31455238 | 0.88 | TDP1 (0.49) | MAPTRAB9ANPC1TLR4TLR2 | |
| SCHEMBL27631548 | 0.83 | ALDH1A1 (0.51) | MAPTRAB9ANPC1ALDH1A1HIF1A | |
| SCHEMBL8302605 | 0.82 | MAPT (0.62) | MAPTRAB9ANPC1TLR4TLR2 | |
| SCHEMBL3031212 | 0.82 | MAPT (0.63) | MAPTRAB9ANPC1TLR4TLR2 | |
| SCHEMBL6974757 | 0.82 | AURKB (0.50) | MAPTRAB9ANPC1TLR4TLR2 | |
| SCHEMBL12643379 | 0.82 | MAPT (0.69) | MAPTRAB9ANPC1TLR4TLR2 | |
| SCHEMBL1237443 | 0.79 | TLR4 (0.49) | MAPTRAB9ANPC1TLR4TLR2 | |
| SCHEMBL13736898 | 0.79 | MAPT (0.49) | MAPTRAB9ANPC1TLR4TLR2 | |
| SCHEMBL9587022 | 0.79 | MAPT (0.41) | MAPTRAB9ANPC1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040152-A1 | HETEROYCLYLPHENYL-AND HETEROCYCLYLPYRIDYL-SUBSTITUTED AZOLECARBOXAMIDES AS HERBICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-05-06 | — | — | WO | disclosed |