Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 16/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25315369 | 0.90 | MAPT (0.64) | MAPTMAPK1MEN1KMT2ATDP1 | |
| SCHEMBL29524516 | 0.90 | MAPT (0.64) | MAPTMAPK1MEN1KMT2ATDP1 | |
| SCHEMBL21588984 | 0.84 | MAPT (0.55) | MAPTMAPK1MEN1KMT2ATDP1 | |
| SCHEMBL8346062 | 0.82 | PRKDC (0.63) | MAPTMAPK1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL16071546 | 0.79 | MAPT (0.62) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL1844193 | 0.79 | MAPT (0.74) | MAPTMAPK1MEN1KMT2ATDP1 | |
| SCHEMBL29523841 | 0.79 | MAPT (0.63) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL12466626 | 0.79 | MAPT (0.63) | MAPTMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL31455388 | 0.78 | PRMT1 (0.46) | MAPTMAPK1MEN1KMT2ATDP1 | |
| SCHEMBL31144715 | 0.78 | PRMT1 (0.46) | MAPTMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |