Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455424 | 0.86 | NPC1 (0.44) | PRMT1MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL31144715 | 0.86 | PRMT1 (0.46) | PRMT1MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL31455489 | 0.86 | PRMT1 (0.46) | PRMT1NPC1RAB9AALDH1A1HTT | |
| SCHEMBL30573735 | 0.80 | ALDH1A1 (0.64) | MAPK1NPC1RAB9AALDH1A1GLA | |
| SCHEMBL12207039 | 0.79 | HTT (0.52) | PRMT1MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL31455242 | 0.78 | MAPT (0.61) | MAPK1ALDH1A1HTTMAPTLMNA | |
| SCHEMBL31455743 | 0.78 | MAPK1 (0.48) | MAPK1FBP1MEN1KMT2AAKR1B1 | |
| SCHEMBL31144701 | 0.76 | EGFR (0.43) | ALDH1A1MAPTFBP1MEN1KMT2A | |
| SCHEMBL10176299 | 0.76 | SMN1; SMN2 (0.54) | MAPK1NPC1RAB9AHTTMAPT | |
| SCHEMBL20045617 | 0.76 | RAB9A (0.60) | PRMT1MAPK1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |