⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4703252 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL31455480 | 0.72 | — | — | |
| SCHEMBL11814482 | 0.70 | — | — | |
| SCHEMBL21404117 | 0.68 | — | — | |
| SCHEMBL10601665 | 0.68 | UGT2B7 (0.31) | — | |
| SCHEMBL15255691 | 0.65 | — | — | |
| SCHEMBL3236611 | 0.64 | APLNR (0.31) | — | |
| SCHEMBL3236600 | 0.64 | APLNR (0.31) | — | |
| SCHEMBL26361642 | 0.64 | APLNR (0.31) | — | |
| SCHEMBL15565744 | 0.64 | CYP3A4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |