Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PORCN | Q9H237 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 3/20 | 0.33 |
| ▸ | BECN1 | Q14457 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420343 | 0.84 | PRMT1 (0.41) | PRMT1GSK3BCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL31455818 | 0.83 | PRMT1 (0.41) | PRMT1GSK3BDYRK1ACYP1A2CYP2C19 | |
| SCHEMBL31455292 | 0.83 | PRMT1 (0.41) | PRMT1GSK3BDYRK1ACYP1A2CYP2C19 | |
| SCHEMBL31455428 | 0.82 | FGFR4 (0.44) | PRMT1CYP1A2CYP2C19CYP2C9MAPT | |
| SCHEMBL31455339 | 0.82 | ABL1 (0.45) | PORCNCYP2D6GSK3BDYRK1AMAPT | |
| SCHEMBL31455563 | 0.82 | PRMT1 (0.43) | PRMT1GSK3BCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL31455251 | 0.82 | PRMT1 (0.43) | PRMT1GSK3BCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL31455040 | 0.80 | PRMT1 (0.40) | PRMT1GSK3BDYRK1ACYP1A2CYP2C19 | |
| SCHEMBL31455417 | 0.80 | PRMT1 (0.39) | CYP2D6PRMT1GSK3BDYRK1ACYP1A2 | |
| SCHEMBL31455246 | 0.79 | BRD4 (0.37) | PORCNCYP2D6GSK3BCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |