Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | PORCN | Q9H237 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CD63 | P08962 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31420362 | 0.79 | GSK3B (0.47) | MAPTMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL31455392 | 0.79 | PORCN (0.41) | BRD4MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL31455289 | 0.78 | PIK3CA (0.46) | BRD4MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL31455339 | 0.76 | ABL1 (0.45) | MAPTKMT2AGSK3BPORCNCYP2D6 | |
| SCHEMBL31455066 | 0.74 | FLT3 (0.41) | BRD4MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL31455353 | 0.74 | MAPT (0.38) | MAPTMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL31455438 | 0.74 | FLT3 (0.44) | BRD4MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL31455381 | 0.65 | GSK3B (0.47) | MAPTMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL31455855 | 0.64 | IDO1 (0.45) | MAPTMEN1KMT2AEGFR | |
| SCHEMBL29310766 | 0.64 | TNF (0.47) | BRD4MAPTMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |