Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP11A1 | P05108 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035682 | 0.85 | CYP19A1 (0.57) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL19074638 | 0.76 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL26113825 | 0.73 | CYP19A1 (0.43) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL30955766 | 0.73 | CYP19A1 (0.70) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL19585699 | 0.73 | CYP19A1 (0.70) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL30828418 | 0.73 | CYP19A1 (0.70) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL6397534 | 0.73 | CYP19A1 (0.37) | CYP19A1 | |
| SCHEMBL27035567 | 0.70 | CYP19A1 (0.49) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL3037963 | 0.69 | CYP19A1 (0.33) | CYP19A1 | |
| SCHEMBL31455157 | 0.69 | CYP2C19 (0.47) | PMP22PDE4DPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |