Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PDE6A | P16499 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455250 | 0.77 | CYP2C19 (0.53) | CYP2C19TSHRCYP2D6LMNACYP1A2 | |
| SCHEMBL2960872 | 0.71 | CYP2C19 (0.78) | CYP2C19TSHRCYP2D6LMNACYP1A2 | |
| SCHEMBL2329572 | 0.71 | CYP2C19 (0.53) | CYP2C19TSHRCYP2D6LMNACYP1A2 | |
| SCHEMBL31455435 | 0.69 | CYP19A1 (0.61) | PDE4DPDE3APMP22 | |
| SCHEMBL3235304 | 0.68 | CYP2C19 (0.53) | CYP2C19TSHRCYP2D6LMNACYP1A2 | |
| SCHEMBL10776342 | 0.67 | CYP2C19 (0.51) | CYP2C19TSHRCYP2D6LMNACYP1A2 | |
| SCHEMBL43183 | 0.67 | TSHR (0.74) | CYP2C19TSHRCYP2D6LMNACYP1A2 | |
| SCHEMBL2324699 | 0.67 | CYP2C19 (0.51) | CYP2C19TSHRCYP2D6LMNACYP1A2 | |
| SCHEMBL11136763 | 0.66 | CYP2C19 (1.00) | CYP2C19TSHRCYP2D6LMNACYP1A2 | |
| SCHEMBL17460821 | 0.66 | CYP2C19 (0.70) | CYP2C19TSHRCYP2D6LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |