Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455503 | 0.81 | ABCG2 (0.38) | ABCG2HTTMAP2K3GSK3BMEN1 | |
| SCHEMBL31420324 | 0.80 | ABCG2 (0.40) | ABCG2AURKAAURKBABCC1GSK3B | |
| SCHEMBL12100934 | 0.78 | GSK3B (0.57) | ABCG2AURKAABCB1GSK3BMEN1 | |
| SCHEMBL31455712 | 0.77 | TSHR (0.42) | ABCG2HTTGSK3BMEN1KMT2A | |
| SCHEMBL7835308 | 0.76 | GALR2 (0.46) | ABCG2HTTGSK3BMEN1KMT2A | |
| SCHEMBL31455004 | 0.75 | ABCG2 (0.40) | ABCG2ABCC1HTTGSK3BMEN1 | |
| SCHEMBL6614664 | 0.74 | ALDH1A1 (0.51) | ABCG2MEN1KMT2APSMD14PRKACA | |
| SCHEMBL31420362 | 0.74 | GSK3B (0.47) | ABCG2AURKAABCB1GSK3BMEN1 | |
| SCHEMBL25386272 | 0.73 | MAPT (0.45) | ABCG2AURKAABCC1GSK3BMAPT | |
| SCHEMBL6618672 | 0.72 | ALDH1A1 (0.55) | AURKAHTTMAP2K3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |