Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31456002 | 0.88 | MEN1 (0.49) | MEN1KMT2ARECQLPOLBSMN1; SMN2 | |
| SCHEMBL31455675 | 0.86 | MAPT (0.54) | MEN1KMT2ARECQLPOLBSMN1; SMN2 | |
| SCHEMBL31455832 | 0.85 | F10 (0.47) | MEN1KMT2AF10POLBSMN1; SMN2 | |
| SCHEMBL31455726 | 0.85 | MAPT (0.49) | MEN1KMT2ARECQLPOLBSMN1; SMN2 | |
| SCHEMBL31455534 | 0.84 | MEN1 (0.47) | MEN1KMT2ARECQLPOLBSMN1; SMN2 | |
| SCHEMBL31455389 | 0.84 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2MITFMAPT | |
| SCHEMBL31455202 | 0.82 | KDR (0.44) | MEN1KMT2ASMN1; SMN2MITFNPC1 | |
| SCHEMBL3492902 | 0.80 | MAPT (0.52) | MEN1KMT2APOLBSMN1; SMN2MITF | |
| SCHEMBL3494240 | 0.77 | AKR1C3 (0.57) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL31455529 | 0.77 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2MITFMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |