Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.44 |
| ▸ | BRAF | P15056 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455523 | 0.88 | ABL1 (0.50) | KMT2ANPC1TP53PKMRAB9A | |
| SCHEMBL31455231 | 0.86 | KDR (0.46) | KDRBRAFKMT2ANPC1TP53 | |
| SCHEMBL31455162 | 0.85 | KMT2A (0.42) | BRAFKMT2ANPC1TP53PKM | |
| SCHEMBL31455603 | 0.82 | MEN1 (0.45) | KMT2ANPC1TP53RAB9AMEN1 | |
| SCHEMBL31455389 | 0.81 | MEN1 (0.43) | KMT2ATP53MEN1MITFSMN1; SMN2 | |
| SCHEMBL31455529 | 0.75 | MEN1 (0.43) | KMT2ANPC1TP53RAB9AABL1 | |
| SCHEMBL31455494 | 0.75 | HDAC1 (0.44) | KMT2ANPC1TP53PKMRAB9A | |
| SCHEMBL31455084 | 0.71 | MAPT (0.39) | KMT2ANPC1TP53PKMRAB9A | |
| SCHEMBL31456002 | 0.70 | MEN1 (0.49) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL31455499 | 0.70 | MAPT (0.39) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |