Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | ACACB | O00763 | 5/20 | 0.38 |
| ▸ | ACACA | Q13085 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455653 | 0.86 | ABCG2 (0.39) | ABCG2BRD4ACACBACACAKDM4A | |
| SCHEMBL31455275 | 0.84 | BRD9 (0.43) | ABCG2BRD4EGFRAURKBSYK | |
| SCHEMBL31455225 | 0.76 | NPC1 (0.44) | ABCG2SYKHDAC1 | |
| SCHEMBL31455195 | 0.74 | HDAC1 (0.45) | ABCG2BRD4AURKBSYKHDAC1 | |
| SCHEMBL4597727 | 0.74 | AKR1B1 (0.46) | BRD4KDM4AHDAC1GRM2 | |
| SCHEMBL14951118 | 0.72 | RAD51 (0.49) | KDM4A | |
| SCHEMBL17109509 | 0.72 | AKT1 (0.43) | ABCG2BRD4ACACBACACAJAK2 | |
| SCHEMBL17109515 | 0.70 | BRD4 (0.49) | ABCG2BRD4ACACBHDAC1 | |
| SCHEMBL31420320 | 0.70 | BRD4 (0.49) | ABCG2BRD4ACACBHDAC1 | |
| SCHEMBL506706 | 0.69 | KDM4A (0.44) | KDM4AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059562-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |