Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27002114 | 0.92 | HMGCR (0.42) | HMGCRTAAR1ALDH1A1KDM4ETDP1 | |
| SCHEMBL27187213 | 0.92 | HMGCR (0.42) | HMGCRTAAR1ALDH1A1KDM4ETDP1 | |
| SCHEMBL27002021 | 0.91 | HTR2A (0.42) | ALDH1A1KDM4EMAPTCYP3A4LMNA | |
| SCHEMBL27187236 | 0.90 | HMGCR (0.40) | HMGCRTAAR1ALDH1A1KDM4ETDP1 | |
| SCHEMBL27187233 | 0.90 | HMGCR (0.40) | HMGCRTAAR1ALDH1A1KDM4ETDP1 | |
| SCHEMBL27188071 | 0.84 | HMGCR (0.42) | HMGCRTAAR1ALDH1A1KDM4ETDP1 | |
| SCHEMBL27002091 | 0.84 | HMGCR (0.42) | HMGCRTAAR1ALDH1A1KDM4ETDP1 | |
| SCHEMBL26611525 | 0.84 | HTR2A (0.44) | TAAR1ALDH1A1KDM4EMAPTCYP3A4 | |
| SCHEMBL26611529 | 0.84 | HTR2A (0.44) | TAAR1ALDH1A1KDM4EMAPTCYP3A4 | |
| SCHEMBL27187239 | 0.82 | TAAR1 (0.41) | TAAR1ALDH1A1KDM4ETDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059373-A1 | NOVEL PHENALKYLAMINES AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |