Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.40 |
| ▸ | CBFB | Q13951 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455983 | 0.83 | CA1 (0.51) | CYP3A4DPP4TAAR1ALDH1A1CA1 | |
| SCHEMBL17722574 | 0.81 | CYP4F2 (0.54) | CYP3A4DPP4TAAR1ALDH1A1KMT2A | |
| SCHEMBL31116543 | 0.81 | DPP4 (0.48) | CYP3A4DPP4ALDH1A1KMT2AKDM4E | |
| SCHEMBL2064203 | 0.81 | DPP4 (0.48) | DPP4ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL31395505 | 0.79 | EGFR (0.51) | DPP4ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL21455751 | 0.79 | ALDH1A1 (0.53) | DPP4ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL30482840 | 0.79 | ALDH1A1 (0.53) | DPP4ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL5309200 | 0.79 | TAAR1 (0.65) | TAAR1 | |
| SCHEMBL14570472 | 0.79 | TAAR1 (0.65) | TAAR1 | |
| SCHEMBL8282635 | 0.79 | CYP3A4 (0.51) | CYP3A4DPP4TAAR1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059373-A1 | NOVEL PHENALKYLAMINES AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |