Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 10/20 | 0.58 |
| ▸ | AURKA | O14965 | 2/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.55 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.52 |
| ▸ | AXL | P30530 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937114 | 0.85 | SYK (0.57) | SYKKITFLT3 | |
| Hydrochloric Acid SCHEMBL3145550 | 0.85 | SYK (0.54) | SYKLRRK2KITFLT3PTK2 | |
| SCHEMBL3135192 | 0.84 | SYK (0.56) | SYKAURKAKITFLT3 | |
| SCHEMBL3150023 | 0.84 | AURKA (0.61) | SYKAURKAKITFLT3AURKB | |
| SCHEMBL13300601 | 0.80 | EGFR (0.61) | AURKALRRK2PTK2AXL | |
| SCHEMBL3814175 | 0.78 | SYK (0.56) | SYKLRRK2 | |
| SCHEMBL4281514 | 0.77 | AURKB (0.54) | SYKAURKALRRK2AURKB | |
| SCHEMBL578664 | 0.77 | AURKB (0.54) | SYKAURKALRRK2AURKB | |
| SCHEMBL3265411 | 0.77 | AURKA (0.52) | SYKAURKALRRK2 | |
| SCHEMBL3136804 | 0.76 | JAK2 (0.65) | SYKAURKALRRK2FLT3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081679-A1 | DIAMINOPYRIMIDINES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-04-01 | — | — | US | disclosed |
| EP-2129222-A1 | DIAMINOPYRIMIDINES AS FUNGICIDES | Bayer CropScience AG (DE) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008107096-A1 | DIAMINOPYRIMIDINES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2008-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081679-A1 | DIAMINOPYRIMIDINES AS FUNGICIDES | PM20D2, DDT, DDX41 | SYK 1098/4885AURKA 2466/4885LRRK2 3855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.